|
KMID : 0931320210210040322
|
|
대한상부위장관.헬리코박터학회지
2021 Volume.21 No. 4 p.322 ~ p.332
|
|
|
In situ Diagnosis of Helicobacter pylori Infection Using the Endoscopic Kyoto Scoring System
|
|
Lim Eun-Sun
Jo Ik-Hyun
Kim Yeon-Ji
Chung Woo-Chul
|
|
|
Abstract
|
|
|
Background/Aims: This study aimed to investigate the possibility of in situ diagnosis of Helicobacter pylori (H. pylori) infection during endoscopic examination. The predictive infection value was estimated using the endoscopic Kyoto scoring system (EKSS), and specific endoscopic findings were evaluated for diagnosing H. pylori infection in H. pylori naive patients and those with a eradication history.
Materials and Methods: A total of 836 patients with H. pylori infection were analyzed. The state of the infection was predicted using the EKSS and specific endoscopic findings.
Results: Patients were classified into two groups: the H. pylori naive group and the group with a the bacterial eradication history. The area under the curve (AUC) on receiver operating characteristics analysis was 0.90 for EKSS in H. pylori naive patients and 0.83 for the other group patients. For patients with open type atrophy and/or intestinal metaplasia, EKSS (24.4%; 95% CI, 12.4~0.3%) and regular arrangement of collecting venules (RAC) (46.3%; 95% CI, 30.7~62.9%) showed low specificities. Mucosal swelling (66.2%; 95% CI, 62.5~69.7%) and sticky mucus (80.5%; 95% CI, 74.8~85.2%) presented relatively high positive predictive values for H. pylori infection in naive patients, whereas reflux esophagitis, hematin, red streak, and duodenitis exhibited high negative predictive values in patients with a H. pylori eradication history (98.0%; 95% CI, 96.4~99.1%).
Conclusions: EKSS and RAC are excellent tools for predicting H. pylori infection. However, they have a limited role in patients with open type atrophy and/or intestinal metaplasia. Specific endoscopic findings could help predict the infection state.
|
|
|
KEYWORD
|
|
|
Diagnosis, Endoscopy, Helicobacter pylori
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|
|